Ubiquitination in the antiviral immune response.

  title={Ubiquitination in the antiviral immune response.},
  author={Meredith E. Davis and Michaela U Gack},
Ubiquitination has long been known to regulate fundamental cellular processes through the induction of proteasomal degradation of target proteins. More recently, 'atypical' non-degradative types of polyubiquitin chains have been appreciated as important regulatory moieties by modulating the activity or subcellular localization of key signaling proteins. Intriguingly, many of these non-degradative types of ubiquitination regulate the innate sensing pathways initiated by pattern recognition… CONTINUE READING
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Ubiquitination in the antiviral immune response

  • M. E. Davis, M. U. Gack
  • Virology
  • 2015

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