Ubiquitin-proteasome system and hereditary cardiomyopathies.


Adequate protein turnover is essential for cardiac homeostasis. Different protein quality controls are involved in the maintenance of protein homeostasis, including molecular chaperones and co-chaperones, the autophagy-lysosomal pathway, and the ubiquitin-proteasome system (UPS). In the last decade, a series of evidence has underlined a major function of… (More)
DOI: 10.1016/j.yjmcc.2013.12.016


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