Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export.

Abstract

The evolutionarily conserved mRNA export receptor Mex67/NXF1 associates with mRNAs through its adaptor, Yra1/REF, allowing mRNA ribonucleoprotein (mRNP) exit through nuclear pores. However, alternate adaptors should exist, since Yra1 is dispensable for mRNA export in Drosophila and Caenorhabditis elegans. Here we report that Mex67 interacts directly with… (More)
DOI: 10.1101/gad.583310

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