Ubiquitin-like proteins.

@article{Veen2012UbiquitinlikeP,
  title={Ubiquitin-like proteins.},
  author={Annemarthe G van der Veen and Hidde L. Ploegh},
  journal={Annual review of biochemistry},
  year={2012},
  volume={81},
  pages={323-57}
}
The eukaryotic ubiquitin family encompasses nearly 20 proteins that are involved in the posttranslational modification of various macromolecules. The ubiquitin-like proteins (UBLs) that are part of this family adopt the β-grasp fold that is characteristic of its founding member ubiquitin (Ub). Although structurally related, UBLs regulate a strikingly diverse set of cellular processes, including nuclear transport, proteolysis, translation, autophagy, and antiviral pathways. New UBL substrates… CONTINUE READING

From This Paper

Topics from this paper.
88 Citations
249 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 88 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 249 references

Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier

  • AG Van der Veen, K Schorpp, C Schlieker, L Buti, JR Damon
  • Proc. Natl. Acad. Sci. USA
  • 2011
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…