Ubiquitin-like proteins.

  title={Ubiquitin-like proteins.},
  author={Annemarthe G van der Veen and Hidde L. Ploegh},
  journal={Annual review of biochemistry},
The eukaryotic ubiquitin family encompasses nearly 20 proteins that are involved in the posttranslational modification of various macromolecules. The ubiquitin-like proteins (UBLs) that are part of this family adopt the β-grasp fold that is characteristic of its founding member ubiquitin (Ub). Although structurally related, UBLs regulate a strikingly diverse set of cellular processes, including nuclear transport, proteolysis, translation, autophagy, and antiviral pathways. New UBL substrates… CONTINUE READING

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Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier

  • AG Van der Veen, K Schorpp, C Schlieker, L Buti, JR Damon
  • Proc. Natl. Acad. Sci. USA
  • 2011
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