Ubiquitin-like proteins: new wines in new bottles.

  title={Ubiquitin-like proteins: new wines in new bottles.},
  author={Edward T. H. Yeh and L F Gong and Tetsu Kamitani},
  volume={248 1-2},
Ubiquitin is a small polypeptide that covalently modifies other cellular proteins and targets them to the proteasome for degradation. In recent years, ubiquitin-dependent proteolysis has been demonstrated to play a critical role in the regulation of many cellular processes, such as cell cycle progression, cell signaling, and immune recognition. The recent discovery of three new ubiquitin-like proteins, NEDD8, Sentrin/SUMO, and Apg12, has further broadened the horizon of this type of post… CONTINUE READING
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