Ubiquitin ligase Rsp5p is involved in the gene expression changes during nutrient limitation in Saccharomyces cerevisiae.

@article{Cardona2009UbiquitinLR,
  title={Ubiquitin ligase Rsp5p is involved in the gene expression changes during nutrient limitation in Saccharomyces cerevisiae.},
  author={Fernando Cardona and Agust{\'i}n Aranda and Marcel-l{\'i} del Olmo},
  journal={Yeast},
  year={2009},
  volume={26 1},
  pages={1-15}
}
Rsp5p is an essential ubiquitin ligase involved in many different cellular events, including amino acid transporters degradation, transcription initiation and mRNA export. It plays important role in both stress resistance and adaptation to the change of nutrients. We have found that ubiquitination machinery is necessary for the correct induction of the stress response SPI1 gene at the entry of the stationary phase. SPI1 is a gene whose expression is regulated by the nutritional status of the… CONTINUE READING

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