Ubiquitin immunoreactivity in cerebrospinal fluid after traumatic brain injury: clinical and experimental findings.

@article{Majetschak2005UbiquitinII,
  title={Ubiquitin immunoreactivity in cerebrospinal fluid after traumatic brain injury: clinical and experimental findings.},
  author={Matthias Majetschak and David R. King and Ulrich Krehmeier and Lissette T Busby and C. Thom{\'e} and Susanne L Vajkoczy and Kenneth G. Proctor},
  journal={Critical care medicine},
  year={2005},
  volume={33 7},
  pages={1589-94}
}
OBJECTIVE Recent data indicate that ubiquitin is increased in serum after trauma and might regulate immune functions. Its cellular source is unknown. Because there have been no previous studies after traumatic brain injury (TBI), we determined whether ubiquitin immunoreactivity is increased in cerebrospinal fluid (CSF) after TBI. DESIGN AND SETTING Prospective observational study of patients, with a subsequent interventional study of animals. SUBJECTS The subjects were 14 patients with TBI… CONTINUE READING

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