Ubiquitin-binding domains

@article{Hicke2005UbiquitinbindingD,
  title={Ubiquitin-binding domains},
  author={Linda A Hicke and Heidi L. Schubert and Christopher P. Hill},
  journal={Nature Reviews Molecular Cell Biology},
  year={2005},
  volume={6},
  pages={610-621}
}
Ubiquitin-binding domains (UBDs) are a collection of modular protein domains that non-covalently bind to ubiquitin. These recently discovered motifs interpret and transmit information conferred by protein ubiquitylation to control various cellular events. Detailed molecular structures are known for a number of UBDs, but to understand their mechanism of action, we also need to know how binding specificity is determined, how ubiquitin binding is regulated, and the function of UBDs in the context… 

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  • Ruofan Yang
  • Biology
    IOP Conference Series: Materials Science and Engineering
  • 2020
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