Ubiquinone-10 production using Agrobacterium tumefaciens dps gene in Escherichia coli by coexpression system.

@article{Zhang2007Ubiquinone10PU,
  title={Ubiquinone-10 production using Agrobacterium tumefaciens dps gene in Escherichia coli by coexpression system.},
  author={Dawei Zhang and Binaya Lal Shrestha and Zhaopeng Li and Tianwei Tan},
  journal={Molecular biotechnology},
  year={2007},
  volume={35 1},
  pages={1-14}
}
Ubiquinone (Coenzyme Q; abbreviation, UQ) acts as a mobile component of the respiratory chain by playing an essential role in the electron transport system, and has been widely used in pharmaceuticals. The biosynthesis of UQ involves 10 sequential reactions brought about by various enzymes. In this study we have cloned, expressed the decaprenyl diphosphate synthase, designated dps gene, from Agrobacterium tumefaciens, and succeeded in detecting UQ-10 in addition to innate UQ-8 in Escherichia… CONTINUE READING

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