Ubiquinone-10 content in lymphocytes of phenylketonuric patients.

@article{Colom2002Ubiquinone10CI,
  title={Ubiquinone-10 content in lymphocytes of phenylketonuric patients.},
  author={Catrina Colom{\'e} and Rafael Artuch and Mar{\'i}a Ant{\`o}nia Vilaseca and Cristina Sierra and N{\'u}ria Brandi and Francisco Jos{\'e} Cambra and Nilo Lambruschini and Jaume Campistol},
  journal={Clinical biochemistry},
  year={2002},
  volume={35 1},
  pages={81-4}
}
OBJECTIVES To investigate the ubiquinone-10 content in lymphocytes from phenylketonuric patients. DESIGN AND METHODS We compared 23 patients with 25 age-matched controls. Ubiquinone-10 was analyzed by HPLC with electrochemical detection. RESULTS Ubiquinone-10 concentrations were significantly lower in patients (77-270 nmol/g of protein) compared with controls (190-550) (p < 0.001). Significantly negative correlation was observed between ubiquinone-10 and phenylalanine (r = -0.441; p < 0.05… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Similar Papers

Loading similar papers…