Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p.

  title={Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p.},
  author={Erica S. Johnson and G{\"u}nter Blobel},
  journal={The Journal of biological chemistry},
  volume={272 43},
At least one essential function of Smt3p, a Saccharomyces cerevisiae ubiquitin-like protein similar to the mammalian protein SUMO-1, involves its posttranslational covalent attachment to other proteins. Using Smt3p affinity chromatography, we have isolated the second enzyme of the Smt3p conjugation pathway and have found that it is identical to Ubc9p, a previously identified protein that has extensive sequence similarity to the ubiquitin-conjugating enzymes (E2s) and that is required for yeast… CONTINUE READING
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