UVB radiation preferentially induces recruitment of memory CD4+ T cells in normal human skin: long-term effect after a single exposure.

@article{Nuzzo1998UVBRP,
  title={UVB radiation preferentially induces recruitment of memory CD4+ T cells in normal human skin: long-term effect after a single exposure.},
  author={S Di Nuzzo and Regien M. R. Sylva-Steenland and Menno A. de Rie and P K Das and J D Bos and Marcel B. M. Teunissen},
  journal={The Journal of investigative dermatology},
  year={1998},
  volume={110 6},
  pages={978-81}
}
Acute, low-doses of ultraviolet (UV)-B radiation affect the immune competent cells of the skin immune system. In this study, we examined the time-dependent changes of the cutaneous T cell population in normal human volunteers following a single local exposure to UV. Solar-simulated UV radiation caused an initial decrease in intraepidermal T cell numbers, even leading to T cell depletion at day 4, whereupon a considerable infiltration of T cells in the epidermis occurred that peaked at day 14… CONTINUE READING