UV irradiation augments lymphoid malignancies in mice with one functional copy of wild-type p53.

@article{Jiang2001UVIA,
  title={UV irradiation augments lymphoid malignancies in mice with one functional copy of wild-type p53.},
  author={W Jiang and Honnavara N. Ananthaswamy and Hans Konrad Muller and Allal Ouhtit and Svetlana Bolshakov and Stephen E. Ullrich and A El-naggar and Margaret L. Kripke},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2001},
  volume={98 17},
  pages={9790-5}
}
Epidemiological studies have suggested an association between exposure to solar UV radiation and the incidence of lymphoid malignancies, which has increased substantially worldwide during the last two decades. Findings from animal studies have raised the question of whether UV radiation might influence the development of lymphoid malignancies by means of its immunosuppressive effect. In this study, we examined the effect of UV irradiation on the development of lymphoid malignancies in mice with… CONTINUE READING
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