UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences.

@article{Scott2001UVIN,
  title={UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences.},
  author={Matthew Scott and Fortin Boisvert and Diego Vieyra and Randal N. Johnston and D. P. Bazett-Jones and Karl T. Riabowol},
  journal={Nucleic acids research},
  year={2001},
  volume={29 10},
  pages={2052-8}
}
The ING1 candidate tumor suppressor is downregulated in a variety of primary tumors and established cancer cell lines. Blocking its expression experimentally promotes unregulated growth in vitro and in vivo, using cell and animal models. Alternative splicing products encode proteins that localize to the nucleus, inhibit cell cycle progression and affect… CONTINUE READING