UV-induced DNA damage and repair: a review.
@article{Sinha2002UVinducedDD, title={UV-induced DNA damage and repair: a review.}, author={R. Sinha and D. H{\"a}der}, journal={Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology}, year={2002}, volume={1 4}, pages={ 225-36 } }
Increases in ultraviolet radiation at the Earth's surface due to the depletion of the stratospheric ozone layer have recently fuelled interest in the mechanisms of various effects it might have on organisms. DNA is certainly one of the key targets for UV-induced damage in a variety of organisms ranging from bacteria to humans. UV radiation induces two of the most abundant mutagenic and cytotoxic DNA lesions such as cyclobutane-pyrimidine dimers (CPDs) and 6-4 photoproducts (6-4PPs) and their… Expand
Figures, Tables, and Topics from this paper
1,346 Citations
Solar ultraviolet radiation-induced DNA damage in aquatic organisms: potential environmental impact.
- Biology, Medicine
- Mutation research
- 2005
- 196
Impact of UV Radiation on Genome Stability and Human Health.
- Chemistry, Medicine
- Advances in experimental medicine and biology
- 2017
- 17
Molecular Mechanisms of Ultraviolet Radiation-Induced DNA Damage and Repair
- Biology, Medicine
- Journal of nucleic acids
- 2010
- 619
- Highly Influenced
- PDF
DNA Damage and Repair in Plants under Ultraviolet and Ionizing Radiations
- Biology, Medicine
- TheScientificWorldJournal
- 2015
- 62
- PDF
The effect of UVA irradiation on the DNA damage response in a human keratinocyte cell line
- Biology
- 2016
- Highly Influenced
- PDF
Photoreactivation is the main repair pathway for UV-induced DNA damage in coral planulae
- Biology, Medicine
- Journal of Experimental Biology
- 2009
- 32
- PDF
Physicochemical mechanism of light-driven DNA repair by (6-4) photolyases.
- Chemistry, Medicine
- Annual review of physical chemistry
- 2014
- 28
References
SHOWING 1-10 OF 226 REFERENCES
Alternative repair pathways for UV‐induced DNA damage
- Medicine, Biology
- BioEssays : news and reviews in molecular, cellular and developmental biology
- 1998
- 77
The DNA damage spectrum produced by simulated sunlight.
- Chemistry, Medicine
- Journal of molecular biology
- 2000
- 153
Dark-repair of ultraviolet-induced pyrimidine dimers in the DNA of wild carrot protoplasts
- Biology, Medicine
- Nature
- 1975
- 77
An alternative eukaryotic DNA excision repair pathway.
- Biology, Medicine
- Molecular and cellular biology
- 1995
- 57
- PDF
A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiae.
- Biology, Medicine
- Molecular and cellular biology
- 1994
- 53
- PDF