UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: a potential diagnostic technique.

@article{Green1992UVCSO,
  title={UV-C sensitivity of unstimulated and stimulated human lymphocytes from normal and xeroderma pigmentosum donors in the comet assay: a potential diagnostic technique.},
  author={Michael H. L. Green and Jillian E Lowe and Susan A. Harcourt and P Akinluyi and Thomas Rowe and Jennifer Cole and Alexander V. Anstey and Colin F. Arlett},
  journal={Mutation research},
  year={1992},
  volume={273 2},
  pages={137-44}
}
We have studied incision-break formation in unstimulated and stimulated populations of human T-lymphocytes using the comet (single-cell microgel electrophoresis) assay. The frequency of strand breaks 1 h after UV-irradiation appears to be far greater in unstimulated than in stimulated lymphocytes from normal donors and the excess of strand breaks was… CONTINUE READING