USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components

@inproceedings{Ning2017USP26FA,
  title={USP26 functions as a negative regulator of cellular reprogramming by stabilising PRC1 complex components},
  author={Bo Ning and Wei Zhao and Chen Qian and Pinghua Liu and Qingtian Li and Wenyuan Li and Rong-Fu Wang},
  booktitle={Nature Communications},
  year={2017}
}
Despite much progress in the comprehension of the complex process of somatic cell reprogramming, many questions regarding the molecular mechanism of regulation remain to be answered. At present, the knowledge on the negative regulation of reprogramming process is indeed poor in contrary to the identification of positive regulators. Here we report for the first time that ubiquitin-specific protease 26 negatively regulates somatic cell-reprogramming process by stabilizing chromobox (CBX… CONTINUE READING

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