USF1 gene variants, cardiovascular risk, and mortality in European Americans: analysis of two US cohort studies.


OBJECTIVE A common haplotype of the upstream transcription factor 1 gene (USF1) has been associated with decreased susceptibility to familial combined hyperlipidemia (FCHL) and, paradoxically, with increased risk of cardiovascular disease (CVD) and all-cause mortality. METHODS AND RESULTS We assessed associations between USF1 tagSNPs, CVD risk factors… (More)

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