UP3005, a Botanical Composition Containing Two Standardized Extracts of Uncaria gambir and Morus alba, Improves Pain Sensitivity and Cartilage Degradations in Monosodium Iodoacetate-Induced Rat OA Disease Model

@inproceedings{Yimam2015UP3005AB,
  title={UP3005, a Botanical Composition Containing Two Standardized Extracts of Uncaria gambir and Morus alba, Improves Pain Sensitivity and Cartilage Degradations in Monosodium Iodoacetate-Induced Rat OA Disease Model},
  author={Mesfin Yimam and Young-Chul Lee and Tae-Woo Kim and Breanna Moore and Ping Jiao and Mei Hong and Hyun-Jin Kim and Jeong-Bum Nam and Mi-Ran Kim and Jin-Sun Oh and Sabrina Cleveland and Eu-Jin Hyun and Min Ning Chu and Qi Jia},
  booktitle={Evidence-based complementary and alternative medicine : eCAM},
  year={2015}
}
Osteoarthritis (OA) is a multifactorial disease primarily noted by cartilage degradation in association with inflammation that causes significant morbidity, joint pain, stiffness, and limited mobility. Present-day management of OA is inadequate due to the lack of principal therapies proven to be effective in hindering disease progression where symptomatic therapy focused approach masks the actual etiology leading to irreversible damage. Here, we describe the effect of UP3005, a composition… CONTINUE READING

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