UKF-based slow-variable control for firing patterns in CA3 neurons

  title={UKF-based slow-variable control for firing patterns in CA3 neurons},
  author={Jiang Wang and Shanshan Li and Jian Cheng and Tingting Zhao and Xile Wei and Bin Deng},
  journal={2012 24th Chinese Control and Decision Conference (CCDC)},
Epilepsy is commonly considered to be the result of excessive firing of neurons. This paper investigates firing patterns of single-neuron in the hippocampus CA3 area based on the Pinsky-Rinzel (PR) model and uses closed-loop control with slow variable as the feedback parameter to suppress neuronal firing. Unscented Kalman Filter (UKF) is adopted to estimate the slow variables which contain important information of the system from membrane potential. In this paper, we propose the basic control… CONTINUE READING

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Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 10 references

Deep brain stimulation in epilepsy : what is next ?

  • S. J. Schiff
  • Curr . Opin . Neurol .
  • 2010

Computer modelling of epilepsy

  • J. Rinzel Pinsky
  • Nature Reviews Neurosci .
  • 2008

PR _ Intrinsic and network rhythmogenesis in a reduced traub model for CA 3 neurons

  • A. Depaulis Kahane
  • J . Neurosci .
  • 1995

Observing the state of non - linear dynamic systems

  • Y. q. Che J. Wang
  • Int . J . Control
  • 1973

Synchronization Measures of the Scalp EEG Can Discriminate Healthy from Alzheimers Subjects

  • F. L. Chang, M. E. Cohen, D. Hudson, A. J. Szeri
  • Int . J . Neural Syst .

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