UK114, a YjgF/Yer057p/UK114 family protein highly conserved from bacteria to mammals, is localized in rat liver peroxisomes.

@article{Antonenkov2007UK114AY,
  title={UK114, a YjgF/Yer057p/UK114 family protein highly conserved from bacteria to mammals, is localized in rat liver peroxisomes.},
  author={Vasily D. Antonenkov and Steffen Ohlmeier and Raija T. Sormunen and J Kalervo Hiltunen},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={357 1},
  pages={
          252-7
        }
}
Mammalian UK114 belongs to a highly conserved family of proteins with unknown functions. Although it is believed that UK114 is a cytosolic or mitochondrial protein there is no detailed study of its intracellular localization. Using analytical subcellular fractionation, electron microscopic colloidal gold technique, and two-dimensional gel electrophoresis of peroxisomal matrix proteins combined with mass spectrometric analysis we show here that a large portion of UK114 is present in rat liver… CONTINUE READING