UK Iatrogenic Creutzfeldt–Jakob disease: investigating human prion transmission across genotypic barriers using human tissue-based and molecular approaches

@inproceedings{Ritchie2016UKIC,
  title={UK Iatrogenic Creutzfeldt–Jakob disease: investigating human prion transmission across genotypic barriers using human tissue-based and molecular approaches},
  author={Diane L Ritchie and Marcelo A Barria and Alexander H. Peden and Helen M. Yull and James D. Kirkpatrick and Peter Adlard and James W Ironside and Mark W Head},
  booktitle={Acta Neuropathologica},
  year={2016}
}
Creutzfeldt–Jakob disease (CJD) is the prototypic human prion disease that occurs most commonly in sporadic and genetic forms, but it is also transmissible and can be acquired through medical procedures, resulting in iatrogenic CJD (iCJD). The largest numbers of iCJD cases that have occurred worldwide have resulted from contaminated cadaveric pituitary-derived human growth hormone (hGH) and its use to treat primary and secondary growth hormone deficiency. We report a comprehensive, tissue-based… CONTINUE READING
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Prion diseases

MW Head, JW Ironside, +3 authors RW Will
Greenfield’s Neuropathology, • 2015

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