UDP-glucose 4-epimerase isoforms UGE2 and UGE4 cooperate in providing UDP-galactose for cell wall biosynthesis and growth of Arabidopsis thaliana.

@article{Rsti2007UDPglucose4I,
  title={UDP-glucose 4-epimerase isoforms UGE2 and UGE4 cooperate in providing UDP-galactose for cell wall biosynthesis and growth of Arabidopsis thaliana.},
  author={Johannes R{\"o}sti and Christopher J. Barton and Sandra S Albrecht and Paul Dupree and Markus Pauly and Kim Findlay and Keith Roberts and Georg J. Seifert},
  journal={The Plant cell},
  year={2007},
  volume={19 5},
  pages={1565-79}
}
Five Arabidopsis thaliana genes that encode UDP-glucose 4-epimerase (UGE) and represent two ancient plant UGE clades might be involved in the regulation of cell wall carbohydrate biosynthesis. We tested this hypothesis in a genome-wide reverse genetic study. Despite significant contributions of each gene to total UGE activity, none was essential for normal growth on soil. uge2 uge4 displayed dramatic general growth defects, while other mutant combinations were partially aberrant. UGE2 together… CONTINUE READING
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