UCPs — unlikely calcium porters

  title={UCPs — unlikely calcium porters},
  author={Paul S Brookes and N. Parker and Julie A. Buckingham and Antonio Vidal-Puig and Andrew Philip Halestrap and Thomas E. Gunter and David G. Nicholls and Paolo Bernardi and John J. Lemasters and Martin D. Brand},
  journal={Nature Cell Biology},
To the editor: The mitochondrial Ca2+ uniporter (MCU) has been characterized for several decades1, but the molecule responsible for this transport activity is currently unknown. Therefore, a recent Nature Cell Biology paper by Trenker et al.2 reporting a role for uncoupling proteins (UCP2/3) in mitochondrial Ca2+ uniport generated much excitement in the… CONTINUE READING