UAP56 RNA helicase is required for axis specification and cytoplasmic mRNA localization in Drosophila.

@article{Meignin2008UAP56RH,
  title={UAP56 RNA helicase is required for axis specification and cytoplasmic mRNA localization in Drosophila.},
  author={Carine Meignin and Ilan Davis},
  journal={Developmental biology},
  year={2008},
  volume={315 1},
  pages={89-98}
}
mRNA export from the nucleus requires the RNA helicase UAP56 and involves remodeling of ribonucleo-protein complexes in the nucleus. Here, we show that UAP56 is required for bulk mRNA export from the nurse cell nuclei that supply most of the material to the growing Drosophila oocyte and for the organization of chromatin in the oocyte nucleus. Loss of UAP56 function leads to patterning defects that identify uap56 as a spindle-class gene similar to the RNA helicase Vasa. UAP56 is required for the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

Similar Papers

Loading similar papers…