U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking

@article{Schenk1999U69593AK,
  title={U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking},
  author={Susan Schenk and Brian Partridge and Toni Shaun Shippenberg},
  journal={Psychopharmacology},
  year={1999},
  volume={144},
  pages={339-346}
}
Abstract  Rationale: Previous research has shown that kappa-opioid receptor agonists decrease intravenous cocaine self-administration. These agents also block the development of sensitization that occurs following repeated exposure to cocaine, which is thought to be important in the maintenance and reinstatement of compulsive drug-seeking behavior. Objectives: This study was designed to determine the effects of the kappa-opioid receptor agonist, U69593, on the maintenance of cocaine self… 

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...

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