U12-dependent intron splicing in plants.

@article{Simpson2008U12dependentIS,
  title={U12-dependent intron splicing in plants.},
  author={Craig G Simpson and John W. S. Brown},
  journal={Current topics in microbiology and immunology},
  year={2008},
  volume={326},
  pages={61-82}
}
U12-dependent (U12) introns have persisted in the genomes of plants since the ancestral divergence between plants and metazoans. These introns, which are rare, are found in a range of genes that include essential functions in DNA replication and RNA metabolism and are implicated in regulating the expression of their host genes. U12 introns are removed from pre-mRNAs by a U12 intron-specific spliceosome. Although this spliceosome shares many properties with the more abundant U2-dependent (U2… CONTINUE READING

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