U.S. Food and Drug Administration approval: crizotinib for treatment of advanced or metastatic non-small cell lung cancer that is anaplastic lymphoma kinase positive.

@article{Malik2014USFA,
  title={U.S. Food and Drug Administration approval: crizotinib for treatment of advanced or metastatic non-small cell lung cancer that is anaplastic lymphoma kinase positive.},
  author={Shakun M. Malik and Virginia Ellen Maher and Karen E. Bijwaard and Robert L. Becker and Lijun Zhang and Shenghui W Tang and Pengfei Song and Qi Liu and Anshu Marathe and Brenda Gehrke and Whitney S Helms and Diane Hanner and Robert Justice and Richard Pazdur},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2014},
  volume={20 8},
  pages={2029-34}
}
On August 26, 2011, the U.S. Food and Drug Administration (FDA) approved crizotinib (XALKORI Capsules, Pfizer Inc.) for treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) that is anaplastic lymphoma kinase (ALK) positive as detected by an FDA-approved test. The Vysis ALK Break-Apart FISH Probe Kit (Abbott Molecular, Inc.) was approved concurrently. In two multicenter, single-arm trials, patients with locally advanced or metastatic ALK-positive NSCLC… CONTINUE READING
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