Tyrosyl DNA phosphodiesterase 2, an enzyme fit for purpose

Abstract

volume 19 number 12 DeCember 2012 nature structural & molecular biology the Top2 peptide from 5′ termini without the need to remove adjacent nucleotides, thus allowing subsequent ligation of the break without loss of DNA sequence. This is in contrast to alternative nucleolytic approaches to liberate for ligation. The availability of Tdp2 may be particularly… (More)
DOI: 10.1038/nsmb.2455

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