Tyrosine sulfation enhances but is not required for PSGL-1 rolling adhesion on P-selectin.

@article{Rodgers2001TyrosineSE,
  title={Tyrosine sulfation enhances but is not required for PSGL-1 rolling adhesion on P-selectin.},
  author={Stephen D. Rodgers and Raymond T. Camphausen and Daniel A. Hammer},
  journal={Biophysical journal},
  year={2001},
  volume={81 4},
  pages={2001-9}
}
P-selectin glycoprotein ligand-1 (PSGL-1) is a large (240 kDa) glycoprotein found on the surface of nearly all leukocytes. The mature molecule is decorated with multiple N- and O-linked glycans and displays copies of the tetrasaccharide sialyl-Lewis(x) (sLe(X)), as well as a cluster of three tyrosine sulfate (tyr-SO(3)) groups near the N-terminus of the… CONTINUE READING