Tyrosine prevents behavioral and neurochemical correlates of an acute stress in rats.

@article{Reinstein1984TyrosinePB,
  title={Tyrosine prevents behavioral and neurochemical correlates of an acute stress in rats.},
  author={Daniel Reinstein and Hendrik Lehnert and Nicholas A. Scott and R. J. Wurtman},
  journal={Life sciences},
  year={1984},
  volume={34 23},
  pages={
          2225-31
        }
}
Exposure of rats to an acute, uncontrollable stressor can increase brain norepinephrine (NE) turnover and decrease locomotor and exploratory behavior. We examined the ability of exogenous tyrosine, NE's amino acid precursor, to protect rats from developing these neurochemical and behavioral changes when stressed. Animals pretreated with saline or tyrosine (200 mg/kg, i.p.) were subjected to tail shock (15 v, 2 mA, 5 sec/30 sec) or to no shock during a 60-min period. Exposure to shock depleted… CONTINUE READING