Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases

@article{Schwartz1998TyrosinePO,
  title={Tyrosine phosphorylation of the TATA element modulatory factor by the FER nuclear tyrosine kinases},
  author={Y Schwartz and Israel Ben-Dor and Ami Navon and Benny Motro and Uri Nir},
  journal={FEBS Letters},
  year={1998},
  volume={434}
}
The FER locus in the mouse encodes two tyrosine kinases, p94fer and p51ferT. While p94fer accumulates in the cytoplasm and nucleus of most mammalian cells the expression of p51ferT is restricted to the nucleus of meiotic primary spermatocytes. The cellular function of the FER kinases is not understood, nor has a substrate for these enzymes been characterized. To identify putative substrates of p94fer and p51ferT, the two enzymes were used as ‘baits’ in the yeast two‐hybrid screening system… Expand
Cell cycle-dependent nuclear accumulation of the p94fer tyrosine kinase is regulated by its NH2 terminus and is affected by kinase domain integrity and ATP binding.
TLDR
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Cell Cycle-dependent Nuclear Accumulation of the p 94 fer Tyrosine Kinase Is Regulated by Its NH 2 Terminus and Is Affected by Kinase Domain Integrity and ATP Binding 1 Israel
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