Tyrosine phosphorylation of cGMP-gated ion channels is under circadian control in chick retina photoreceptors.

@article{Chae2007TyrosinePO,
  title={Tyrosine phosphorylation of cGMP-gated ion channels is under circadian control in chick retina photoreceptors.},
  author={K. -S. Chae and Gladys Y-P Ko and Stuart E Dryer},
  journal={Investigative ophthalmology & visual science},
  year={2007},
  volume={48 2},
  pages={
          901-6
        }
}
PURPOSE To investigate the role of tyrosine phosphorylation in circadian regulation of cGMP-gated cation channels (CNGCs) of chicken cone photoreceptors. METHODS Chick retinas were studied on the second day of constant darkness (DD) after several days of entrainment to 12:12 hr light-dark (LD) cycles in vitro. Inside-out patch recordings were made during the subjective day and subjective night to quantify circadian changes in the sensitivity of CNGCs to activation by cGMP after treatment with… CONTINUE READING