Tyrosine phosphorylation-dependence of caveolae-mediated endocytosis

  title={Tyrosine phosphorylation-dependence of caveolae-mediated endocytosis},
  author={Maria S Sverdlov and Ayesha N. Shajahan and Richard D Minshall},
  booktitle={Journal of cellular and molecular medicine},
Caveolae are flask-shaped plasma membrane invaginations that mediate endocytosis and transcytosis of plasma macromolecules, such as albumin, insulin and low-density lipoprotein (LDL), as well as certain viruses, bacteria and bacterial toxins. Caveolae-mediated transcytosis of macromolecules is critical for maintaining vascular homeostasis by regulating the oncotic pressure gradient and tissue delivery of drugs, vitamins, lipids and ions. Entrapment of cargo within caveolae induces activation of… CONTINUE READING


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Lung edema and microvascular permeability

  • RD Minshall, SM Vogel
  • Burlington: Elsevier Science,
  • 2006
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