Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking.

@article{Kawakami1994TyrosinePA,
  title={Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking.},
  author={Yuko Kawakami and Libo Yao and Toru Miura and Satoshi Tsukada and Owen N Witte and Toshiaki Kawakami},
  journal={Molecular and cellular biology},
  year={1994},
  volume={14 8},
  pages={5108-13}
}
Tyrosine phosphorylation of several cellular proteins is one of the earliest signaling events induced by cross-linking of the high-affinity receptor for immunoglobulin E (Fc epsilon RI) on mast cells or basophils. Tyrosine kinases activated during this process include the Src family kinases, Lyn, c-Yes, and c-Src, and members of another subfamily, Syk and PTK72 (identical or highly related to Syk). Recently, some of us described two novel tyrosine kinases, Emb and Emt, whose expression was… CONTINUE READING