Tyrosine kinase inhibition in acute myeloid leukemia.

Abstract

Extensive work by many groups over the last two decades has established that tyrosine kinases play critical roles in the proliferation and survival of myeloid leukemia cells. Targeting pathways activated by dysregulated tyrosine kinases in acute myeloid leukemia (AML) or chronic myeloid leukemia (CML) has been a major focus of clinical eff orts for the… (More)
DOI: 10.3109/10428194.2012.754889

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