Tyrosine in position 4 is the key amino acid for the binding of angiotensin II to human arteriolar receptor.

@article{Kno1987TyrosineIP,
  title={Tyrosine in position 4 is the key amino acid for the binding of angiotensin II to human arteriolar receptor.},
  author={T. K{\^o}no and Y. Kiso and M. Khosla and N. Sakura},
  journal={Endocrinologia japonica},
  year={1987},
  volume={34 5},
  pages={
          737-43
        }
}
  • T. Kôno, Y. Kiso, +1 author N. Sakura
  • Published 1987
  • Chemistry, Medicine
  • Endocrinologia japonica
  • In order to detect the portion of the angiotensin II molecule binding to the human arteriolar receptor, angiotensin II-(1-5)-pentapeptide, angiotensin II-(1-4)-tetrapeptide and angiotensin II-(1-3)-tripeptide were infused intravenously as saline solutions into the same 5 normal men from 0900 h at a rate of 30 nmol (20 micrograms)/kg.min (1.2 ml/min) for 15 minutes, at a rate of 90 nmol (54.5 micrograms)/kg.min (3.0 ml/min) for 6 minutes and at a rate of 140 nmol (54.5 micrograms)/kg.min (3.0 ml… CONTINUE READING
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