Tyrosine hydroxylase and dopamine D4 receptor allelic distribution in Scandinavian chronic alcoholics.

@article{Geijer1997TyrosineHA,
  title={Tyrosine hydroxylase and dopamine D4 receptor allelic distribution in Scandinavian chronic alcoholics.},
  author={Th. Geijer and Erik J{\"o}nsson and J C Neiman and Malin Lindhagen Persson and Stefan Brene and Agneta Gyllander and G{\"o}rarl Sedvall and Ulf Rydberg and Danuta Wasserman and Lars Terenius},
  journal={Alcoholism, clinical and experimental research},
  year={1997},
  volume={21 1},
  pages={35-9}
}
Associations of polymorphic genetic markers at the tyrosine hydroxylase (TH) and dopamine D4 receptor (DRD4) loci were examined in Scandinavian chronic alcoholics (n = 72) and control subjects (n = 67). Patients were divided into subgroups with regard to the presence of parental alcoholism and age of onset. Neither the TH nor the DRD4 allele distributions were significantly different when alcoholic samples were compared with control subjects. However, a tendency to high prevalence for 1 of the… CONTINUE READING

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