Tyrosine Improves Working Memory in a Multitasking Environment

  title={Tyrosine Improves Working Memory in a Multitasking Environment},
  author={John R. Thomas and Park Lockwood and Anita Singh and Patricia A. Deuster},
  journal={Pharmacology Biochemistry and Behavior},
Behavioral and cognitive effects of tyrosine intake in healthy human adults
Tyrosine Intake and Cardiovascular Responses in a Motivated Performance Situation
Ingesting the catecholamine precursor tyrosine can prevent decrements in, or improve, cognitive and motor performance in demanding situations. Furthermore, the biopsychosocial model of challenge and
Working Memory Reloaded: Tyrosine Repletes Updating in the N-Back Task
This result suggests that TYR can replete cognitive resources when more control is needed and, more generally, that food can act as a cognitive enhancer.
Neuro-Cognitive Effects of Acute Tyrosine Administration on Reactive and Proactive Response Inhibition in Healthy Older Adults
Tyrosine negatively affected proactive response slowing and associated fronto-striatal activation in an age-dependent manner, highlighting the importance of catecholamines, perhaps particularly dopamine, for proactive response inhibition in older adults.
Baseline-dependent effect of dopamine’s precursor L-tyrosine on working memory gating but not updating
  • B. Jongkees
  • Psychology, Biology
    Cognitive, affective & behavioral neuroscience
  • 2020
The results of this study indicate that updating and gating are differentially affected by a dopaminergic manipulation, and highlights the importance of distinguishing these processes when studying WM, for example, in the context of WM deficits in disorders with a dopamine pathophysiology.


The effects of tyrosine on cognitive performance during extended wakefulness.
Tyrosine administration was associated with a significant amelioration of the usual performance decline on a psychomotor task and a significant reduction in lapse probability on a high-event-rate vigilance task, suggesting that tyrosine is a relatively benign treatment at this dose.
Tyrosine and its potential use as a countermeasure to performance decrement in military sustained operations.
Experimental data in the literature suggest that tyrosine, a precursor of the neurotransmitter norepinephrine, may be useful in counteracting any stress-related performance decrement and mood deterioration in the following way: various forms of stress induce brain depletion of catecholamines, especially nore Pinephrine, in animals.
Repeated exposure to moderate cold impairs matching-to-sample performance.
The data show that even moderate cold exposure that does not produce core hypothermia can impair performance of a complex cognitive task and that the magnitude of performance change is not attenuated by a brief series of cold exposures.
Administration of 1-Tyrosine Prevents Cold-Induced Memory Deficits in Naval Special Warfare Personnel.
The results indicate that consumption of tyrosine prevented cold-induced PAB deficits observed with the placebo group, and on average the subjects who consumed placebo showed performance decrements on acquisition and memory tasks following cold exposure, while theSubjects who consumed tyosine had test scores comparable to those obtained under baseline conditions.