• Medicine
  • Published in Journal of neurochemistry 1994

Tyrosination state of alpha-tubulin in regenerating peripheral nerve.

@article{Mullins1994TyrosinationSO,
  title={Tyrosination state of alpha-tubulin in regenerating peripheral nerve.},
  author={F H Mullins and Alan J. Hargreaves and J. Y. Li and Annica Dahlstr{\"o}m and W. G. Mclean},
  journal={Journal of neurochemistry},
  year={1994},
  volume={62 1},
  pages={
          227-34
        }
}
Certain modifications of the neuronal cytoskeleton that are associated with development also occur during regeneration of adult mammalian peripheral nerve. The aim of the present study was to examine one such modification, the tyrosination of alpha-tubulin. Adult rats were anaesthetized and the left or right sciatic nerve randomly selected and crushed to induce regeneration. In certain instances nerves were crushed then ligatured about the crush, to prevent regeneration. Five days later the… CONTINUE READING

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