Tyrosinase inhibitory constituents from the roots of Morus nigra: a structure-activity relationship study.

  title={Tyrosinase inhibitory constituents from the roots of Morus nigra: a structure-activity relationship study.},
  author={Zong-Ping Zheng and Ka-Wing Cheng and Qin Zhu and Xiachang Wang and Zhi-xiu Lin and Mingfu Wang},
  journal={Journal of agricultural and food chemistry},
  volume={58 9},
The phytochemical profiles of Morus nigra roots and twigs were compared by HPLC with those of the old and young twigs of Morus alba which are known to contain oxyresveratrol and mulberroside A as major components. It was found that M. nigra root extract contains some unknown natural products with potential tyrosinase inhibitory activity. The extract (95% ethanol) of the roots of M. nigra was further investigated in this study. One new compound, 5'-geranyl-5,7,2',4'-tetrahydroxyflavone, and… 

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