Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future

@article{Kim2005TyrosinaseIF,
  title={Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future},
  author={Y. Kim and H. Uyama},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2005},
  volume={62},
  pages={1707-1723}
}
  • Y. Kim, H. Uyama
  • Published 2005
  • Chemistry, Medicine
  • Cellular and Molecular Life Sciences CMLS
  • Abstract.Tyrosinase is known to be a key enzyme in melanin biosynthesis, involved in determining the color of mammalian skin and hair. Various dermatological disorders, such as melasma, age spots and sites of actinic damage, arise from the accumulation of an excessive level of epidermal pigmentation. In addition, unfavorable enzymatic browning of plant-derived foods by tyrosinase causes a decrease in nutritional quality and economic loss of food products. The inadequacy of current conventional… CONTINUE READING
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