Tyrosinase as a multifunctional reporter gene for Photoacoustic/MRI/PET triple modality molecular imaging

@inproceedings{Qin2013TyrosinaseAA,
  title={Tyrosinase as a multifunctional reporter gene for Photoacoustic/MRI/PET triple modality molecular imaging},
  author={Chunxia Qin and Kai Cheng and Kai Chen and Xiang Hu and Yang Liu and Xiaoli Lan and Yongxue Zhang and Hongguang Liu and Yingding Xu and Lihong Bu and Xinhui Su and Xiaohua Zhu and Shuxian Meng and Zhen Cheng},
  booktitle={Scientific reports},
  year={2013}
}
Development of reporter genes for multimodality molecular imaging is highly important. In contrast to the conventional strategies which have focused on fusing several reporter genes together to serve as multimodal reporters, human tyrosinase (TYR)--the key enzyme in melanin production--was evaluated in this study as a stand-alone reporter gene for in vitro and in vivo photoacoustic imaging (PAI), magnetic resonance imaging (MRI) and positron emission tomography (PET). Human breast cancer cells… CONTINUE READING
Highly Cited
This paper has 29 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 20 citations

References

Publications referenced by this paper.
Showing 1-10 of 61 references

The authors declare no competing financial interests

  • Z. Cheng, Z. Xiong, +22 authors preparation of the manuscript. Additional information Competin interests
  • License: This work is licensed under a Creative…
  • 2013

In vivo imaging of inducible tyrosinase gene expression with an ultrasound array-based photoacoustic system

  • T. Harrison, R. J. Paproski, R. J. Zemp
  • Photons Plus Ultrasound: Imaging and Sensing 8223…
  • 2012

Proof-of-concept study of monitoring cancer drug therapy with cerenkov luminescence imaging

  • Y Xu
  • J Nucl Med
  • 2012