Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.

Abstract

Tropomyosin-related kinase A (TrkA) receptor mediates the effects exerted by nerve growth factor on several subpopulations of neuronal cells. Ligand binding to TrkA induces receptor autophosphorylation on several tyrosine residues and the activation of signaling cascades. In this study, we describe a new site relevant for TrkA regulation, the tyrosine 701… (More)
DOI: 10.1111/j.1471-4159.2007.05027.x

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