Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.


Tropomyosin-related kinase A (TrkA) receptor mediates the effects exerted by nerve growth factor on several subpopulations of neuronal cells. Ligand binding to TrkA induces receptor autophosphorylation on several tyrosine residues and the activation of signaling cascades. In this study, we describe a new site relevant for TrkA regulation, the tyrosine 701… (More)
DOI: 10.1111/j.1471-4159.2007.05027.x


  • Presentations referencing similar topics