Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: its activation coupled with G0/G1 phase cell cycle arrest.

@article{Mohan2010TyphoniumFI,
  title={Typhonium flagelliforme induces apoptosis in CEMss cells via activation of caspase-9, PARP cleavage and cytochrome c release: its activation coupled with G0/G1 phase cell cycle arrest.},
  author={Syam Mohan and Ahmad Bustamam Hj. Abdul and Siddig Ibrahim Abdelwahab and Adel Sharaf Al-zubairi and Mohamed Aspollah Sukari and Rasedee Abdullah and Manal Mohamed Elhassan Taha and Mohamed Yousif Ibrahim and Suvitha Syam},
  journal={Journal of ethnopharmacology},
  year={2010},
  volume={131 3},
  pages={592-600}
}
ETHNOPHARMACOLOGICAL RELEVANCE The plant Typhonium flagelliforme (TF), commonly known as 'rodent tuber' in Malaysia, is often used as traditional remedy for cancer, including leukemia. AIM OF THE STUDY We had previously identified morphologically that the linoleic acid rich fraction (DCM/F7) from the tubers of this plant induces selective anti-proliferative effects and apoptosis in CEMss cells. In this present study, we subjected the same DCM/F7 fraction to cell based activity analyses in… CONTINUE READING
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