Typhoid fever. Studies of blood coagulation, bacteremia, and endotoxemia.

  title={Typhoid fever. Studies of blood coagulation, bacteremia, and endotoxemia.},
  author={Twiss Butler and William R. Bell and Jack Levin and N N Linh and Kathryn Arnold},
  journal={Archives of internal medicine},
  volume={138 3},
Patients with typhoid fever were studied to determine whether disseminated intravascular coagulation (DIC), circulating bacteria, and endotoxemia were responsible for the signs and symptoms of their illnesses. Coagulation tests in 28 patients detected thrombocytopenia in 17, hypofibrinogenemia in nine, and elevated titers of fibrinogen-related antigens in 20. Repeated testing during convalescence showed a return toward normal values. Intestinal bleeding, however, did not correlate with… CONTINUE READING
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