Types I and III procollagen extension peptides in serum respond to fracture in humans

  title={Types I and III procollagen extension peptides in serum respond to fracture in humans},
  author={S. Joerring and Lars Thorbj\orn Jensen and Gert Rahbek Andersen and Julia Sidenius Johansen},
  journal={Archives of Orthopaedic and Trauma Surgery},
Markers of types I and III collagen turnover were measured in serial blood samples in 16 patients with a Colles' fracture. The collagen markers were the carboxy-terminal extension peptide of type I procollagen (PICP) and the amino-terminal extension peptide of type III procollagen (PIIINP). Significant increases were found of PIIINP within 1 week and of PICP within 2 weeks. This sequential appearance of PIIINP and PICP was found to be in agreement with the appearance of types III and I collagen… CONTINUE READING

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