Type-specific efficacy of acellular pertussis vaccine.

  title={Type-specific efficacy of acellular pertussis vaccine.},
  author={Teruyoshi Aoyama and Yuko Murase and Tsuyoshi Gonda and Tsutomu Iwata},
  journal={American journal of diseases of children},
  volume={142 1},
Two types of acellular pertussis vaccine have been used in Japan since their introduction in 1981. They are different in their antigen content and immunogenicity. To assess the type-specific efficacy of acellular pertussis vaccine commercially available in Japan, 442 households of patients with pertussis were surveyed from 1981 to 1987. The secondary attack rates in children 2 through 8 years of age were 61.3% (46/75) in unimmunized children, 7.5% (4/53) in children fully immunized by the… CONTINUE READING