Type of desmin expression in cardiomyocytes - a good marker of heart failure development in idiopathic dilated cardiomyopathy.

@article{Pawlak2012TypeOD,
  title={Type of desmin expression in cardiomyocytes - a good marker of heart failure development in idiopathic dilated cardiomyopathy.},
  author={Agnieszka Pawlak and Robert Julian Gil and Tomasz Kulawik and Maciej Pronicki and Agnieszka Karkucińska-Więckowska and Tamara Szymańska-Dębińska and Katarzyna Gil and Nikolaj Lagwinski and Elżbieta Czarnowska},
  journal={Journal of internal medicine},
  year={2012},
  volume={272 3},
  pages={287-97}
}
AIM The aim of this study was to determine whether remodelling of the desmin (DES) cytoskeleton affects myocardial function and whether it could be a useful marker of disease progression in patients with idiopathic dilated cardiomyopathy (IDCM). MATERIAL AND METHODS Endomyocardial biopsy was performed in 195 IDCM patients, and five to six specimens were collected from the left ventricle. DES expression was evaluated using tissue immunostaining and Western blotting. The study population was… CONTINUE READING
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