Type XXVII collagen at the transition of cartilage to bone during skeletogenesis.

@article{Hjorten2007TypeXC,
  title={Type XXVII collagen at the transition of cartilage to bone during skeletogenesis.},
  author={Rebecca Hjorten and Uwe J. Hansen and Robert A. Underwood and Helena E Telfer and Russell J. Fernandes and Deborah Krakow and Eiman T Sebald and Sebastian Wachsmann-Hogiu and Peter U Bruckner and Robin Jacquet and William J. Landis and Peter H Byers and James M. Pace},
  journal={Bone},
  year={2007},
  volume={41 4},
  pages={
          535-42
        }
}
COL27A1 is a member of the collagen fibrillar gene family and is expressed in cartilaginous tissues including the anlage of endochondral bone. To begin to understand its role in skeletogenesis, the temporospatial distributions of its RNA message and protein product, type XXVII collagen, were determined in developing human skeletal tissues. Laser capture microdissection and quantitative reverse-transcription polymerase chain reaction demonstrated that gene expression occurred throughout the… CONTINUE READING
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